2026 · Telehealth GLP-1

The 5 best online GLP-1 programs, measured.

Price, medication, speed and ratings, side by side.

UPDATED OCT 15, 2026

We receive compensation from featured providers, which may affect placement and scores. Scores are editorial opinion, not clinical results. Prices are from each provider's site and change often. Not medical advice. Full disclaimer.

Doctor with a stethoscope reviewing a patient request on a smartphone

The leaderboard

Prices as of Oct 15, 2026
RankProviderBest forFromScore
01 Best Overall $249/mo 9.8 Visit
02 Most Options $149 1st mo 9.5 Visit
03 Fastest Delivery From $148 9.2 Visit
04 Best Value $99/mo 9.0 Visit
05 Pay Over Time From $179 8.7 Visit
01 DirectMeds logo directmeds.com
Best Overall

DirectMeds

  • Injections
  • Drops
  • Semaglutide & tirzepatide
  • All-inclusive price, no membership
  • Ships in 1–2 business days
  • Full refund if not approved
  • Compounded only, no brand-name
★ Editor's choice
9.8SCORE
Trustpilot 4.6 · 16.5K
$249/mo
Check Eligibility
02 MEDVi logo medvi.org
Most Options

MEDVi

  • Injections
  • Tablets
  • Wegovy®
  • Zepbound®
  • $149 first month (promo)
  • Tablets or injections
  • Brand-name Wegovy® & Zepbound®
  • 24/7 support, HSA/FSA
  • Refills $299/mo; strict refunds
9.5SCORE
Trustpilot 4.3 · 14.9K
$149 1st mo
See If You Qualify
03 InstaRx logo instarx.com
Fastest Delivery

InstaRx

  • Injections
  • Delivered in as little as 2 days
  • Physician review within 1 day
  • Same flat price at every dose
  • No membership, cancel anytime
  • Injections only
9.2SCORE
No Trustpilot rating yet
From $148
Get Started
04 BrightMeds logo brightmeds.com
Best Value

BrightMeds

  • Injections
  • Zepbound®
  • Lowest price: from $99/mo
  • Any dose, same flat price
  • No consult or membership fees
  • 100% refund if not approved
  • Not available in all states
9.0SCORE
Trustpilot 4.7 · 1K
$99/mo
Check Availability
05 TrimRx logo trimrx.com
Pay Over Time

TrimRx

  • Injections
  • Klarna & Afterpay accepted
  • Price stays fixed as dose changes
  • Free consult & delivery
  • Unlimited check-ins
  • Lower Trustpilot score
8.7SCORE
Trustpilot 3.8 · 5.4K
From $179
Visit TrimRx

Prices from provider sites, Oct 15, 2026; may be promotional. Prescription required. Compounded drugs are not FDA-approved.

Why it's #1

DirectMeds

  • 01One price covers it all: no membership
  • 02Injections or under-the-tongue drops
  • 034.6 on Trustpilot from 16,500+ reviews
Check eligibility
Doctor in a white coat on a video consultation with a patient on a laptop
  1. 15-min online quiz
  2. 2Licensed provider review
  3. 3Shipped to your door

FAQ

Who qualifies?

A licensed clinician decides. Typically adults with a BMI of 30+, or 27+ with a weight-related condition.

Do I need insurance?

No. All five are self-pay, and several accept HSA/FSA.

Compounded vs. brand-name?

Compounded versions cost less but are not FDA-approved. Wegovy® and Zepbound® are FDA-approved.

Side effects?

Most common: nausea, diarrhea and constipation. Rare: pancreatitis and gallbladder issues. Ask your prescriber.

GLP-1 medications are prescription-only and not right for everyone. Do not use if you or a family member had medullary thyroid carcinoma, or if you have MEN 2. Individual results vary. Not medical advice. Wegovy® is a trademark of Novo Nordisk; Zepbound® of Eli Lilly. Full disclaimer

#1 Pick: DirectMedsFrom $249/mo, all-in Check Eligibility